The invention relates to a sensor system based on a superhydrophobic piezoelectric quartz resonator supporting a mode of volumetric electromechanical ("acoustic") vibrations, applicable in the field of chemistry, biology, and medicine, and in particular for qualitative and quantitative analysis of the biochemical components of urine (pH, urea, creatinine, uric acid, etc.). According to the proposed sensor system for complex biochemical analysis of urine, approximately 1 mL of human urine is placed on the upper surface of a 5 MHz quartz microbalance with a carbon black interface coating, and changes in the resonance frequency and dynamic resistance of the quartz microbalance, caused by the rate of wetting of the soot due to the biochemical composition of the liquid are recorded in real time in graphical form by an electronic unit. The main advantage of the described sensor configuration is that the active sensor surface remains in direct contact with the urine, but the non-wetting soot coating allows the recognition of biological molecules whose concentration falls outside the resolution range of a traditional quartz microbalance. The modified sensor system establishes a correlation between quantitative data on complex biochemical indicators of urine, such as pH, protein content, creatinine, urea, and uric acid, and changes in the degree of carbon soot wetting, rather than considering changes in the mass loading of the active zone as a sensory indicator. This increases the sensitivity and resolution of the sensor, since even negligible differences in urine biochemistry cause deviations in the rate of soot wetting and, accordingly, in the type and parameters of the sensor signal, which is a prerequisite for effective diagnosis of kidney diseases. The sensor system based on a superhydrophobic piezoelectric quartz resonator with a carbon soot interface coating can find wide practical application in the field of clinical and veterinary medicine, for qualitative and quantitative analysis of biochemical parameters of human and animal urine, and for the detection of diseases related to the excretory, digestive, and respiratory systems.
