COMPOSITIONS OF FORMS FOR LOCAL APPLICATION ON THE SKIN CONTAINING GINKGO BILOBA SEED EXTRACT OR MIXTURE OF GINKGO BILOBA SEED EXTRACT AND INDIVIDUAL BIOLOGICALLY ACTIVE POLYPHENOLIC COMPOUND

Inventor(s)

Ilia Blagoev Rashkov, Milena Georgieva Ignatova, Nevenka Emanuilova Manolova, Selin Erdinch Kyuchyuk, Yana Nikolaeva Feodorova, Teodora Krumova Tomova, Iva Alexandrova Slavova, Maryana Dimitrova Argirova

Applicant(s)/Owner(s)

MEDICAL UNIVERSITY - PLOVDIV, BG, 4002 Plovdiv, 15A "Vasil Aprilov" str. INSTITUTE OF POLYMERS - BAS, BG, 1113 Sofia, "Acad. Georgi Bonchev" str., bl. 103 A

Application number

Publication number

4109/01.09.2021

Priority date

June 11, 2021

Status

Issued license, type, duration

License holder(s)

Abstract

This utility model relates to compositions of forms for local application on the skin, representing an ointment or patch of electro fibered fibrous material containing Ginkgo biloba seed extract or a mixture of Ginkgo biloba seed extract and individual biologically active polyphenolic compound quercetin, which have antioxidant and anti-tumor properties. These compositions are obtained using beeswax, vegetable oil and a non-ionic water-soluble polymer (polyethylene glycol or polypropylene glycol). The patches may also contain an aliphatic polyester, such as polylactic acid. The resulting ointments or patches of electro fibered fibrous material do not contain organic solvent and parabens and are made from vegetable oils, biocompatible polymers and natural biologically active substances, which makes them suitable for for local application on the skin by people of all ages. These compositions, containing Ginkgo biloba seed extract or a mixture of Ginkgo biloba seed extract and individual biologically active polyphenolic compound, have proven antioxidant and anti-tumor properties and can find application in personalized medicine, pharmacy, cosmetics and others.